How to choose the best anti-dandruff ingredients Climbazole and Piroctone Olamine used in shampoo
Release time: 2024-08-20
When it comes to effective anti-dandruff solutions and scalp care, Climbazole (CAS No.: 38083-17-9, Chemical Formula: C15H17ClN2O2) and Piroctone Olamine(CAS No.: 68890-66-4, Chemical Formula: C16H30N2O3) are two key ingredients widely recognized in the personal care industry. Both are essential in the formulation of shampoos that target dandruff and scalp issues. Understanding the differences between these two ingredients and their correct usage in shampoo production is vital for creating high-quality products that meet consumer needs.
First let us know climbazole and Piroctone Olamine Chemical Structure and Properties
Climbazole: This ingredient is a powerful antifungal agent, particularly effective against Malassezia, the fungus commonly linked to dandruff. Climbazole, with the chemical formula C15H17ClN2O2, works by disrupting the fungal cell membrane, thereby reducing dandruff and related symptoms. In anti-dandruff shampoo formulations, Climbazole is crucial for ensuring that the product effectively combats dandruff and promotes scalp health
Piroctone Olamine: Similar to Climbazole, Piroctone Olamine (C16H30N2O3) possesses antifungal and antibacterial properties. Its mechanism involves interacting with fungal enzymes to inhibit their growth. Shampoos containing Piroctone Olamine are known for their effectiveness in treating and preventing dandruff, making them a preferred choice in the hair care market.
Efficacy and Usage in Shampoo Formulations
Climbazole in Shampoo
Concentration and Usage: Climbazole (CAS No.: 38083-17-9) is typically used in shampoos at a concentration of 0.5% to 1%. This range has been proven effective in clinical studies, significantly reducing dandruff and soothing scalp irritation. At BLi-T (Hefei) Chemical Co., Ltd., we ensure that our Climbazole products are formulated to meet these precise concentrations, delivering optimal results for consumers.
*The content of climbazole from BLIT CHEMICAL is ≥99%, and the content of para-chlorophenol is ≤100PPM, which are the key indicators of climbazole quality.
Formulation Synergy: Climbazole is often combined with mild surfactants like Cocamidopropyl Betaine and Lauryl Glucoside to provide effective cleansing without irritating the scalp. It also pairs well with antioxidants like Vitamin E (Tocopherol) and moisturizers such as Glycerin to enhance the hydrating and soothing effects of the shampoo. By carefully selecting these complementary ingredients, Climbazole can help create a more effective and gentle anti-dandruff shampoo.
Effects: Regular use of shampoos containing Climbazole can lead to a noticeable reduction in dandruff within 2-4 weeks, along with improved scalp condition. Long-term use helps maintain a balanced scalp environment, preventing the recurrence of dandruff.
Piroctone Olamine in Shampoo
Concentration and Usage: The recommended concentration of Piroctone Olamine (CAS No.: 68890-66-4) in shampoos is also between 0.5% and 1%. Within this range, Piroctone Olamine effectively inhibits the growth of dandruff-causing fungi. At BLi-T (Hefei) Chemical Co., Ltd., we focus on precision in our formulations to ensure our Piroctone Olamine products provide consistent and effective results.
During the production process, BLIT CHEMICAL’s Piroctone Olamine is repeatedly purified and crystallized, which makes the Piroctone Olamine we produce have better purity and a purer white appearance. At the same time, the nitrosamine content is ≤50ppb, which is more conducive to the safety of shampoo.
Effects: Shampoos formulated with Piroctone Olamine can effectively reduce dandruff and alleviate associated symptoms like itching and irritation. Consistent use leads to healthier scalp conditions and a noticeable reduction in dandruff.
Considerations in Shampoo Production
Formulation Compatibility
Climbazole: In shampoo formulations, it is important to avoid mixing Climbazole with highly acidic or alkaline ingredients, as these can diminish its antifungal effectiveness. The ideal pH range for Climbazole is between 5 and 6.5. Additionally, to ensure the stability of Climbazole, strong oxidizers should be avoided. At BLi-T (Hefei) Chemical Co., Ltd., we carefully select compatible ingredients to ensure that our Climbazole-based products maintain their efficacy and stability.
Piroctone Olamine: Piroctone Olamine should not be used with high-ionic-strength surfactants, as these may reduce its activity. To extend the product’s shelf life, it is advisable to include stabilizers in the formulation. We at BLi-T (Hefei) Chemical Co., Ltd. pay close attention to these considerations, ensuring our Piroctone Olamine formulations are both effective and long-lasting.
If you need formulation guidance, please contact us at info@blitchem.com
Product Stability
Climbazole: During product development, it is important to consider Climbazole’s sensitivity to light, which can lead to degradation if exposed to direct sunlight for long periods. Proper storage conditions, such as keeping the product in a cool, dry place, are essential for maintaining its effectiveness.
Piroctone Olamine: To preserve the efficacy of Piroctone Olamine, it is important to include antioxidants in the formulation to protect against oxidation. The final product should be stored away from high temperatures and humidity. At BLi-T (Hefei) Chemical Co., Ltd., we prioritize the stability of our products to ensure they meet the highest standards.
In order to ensure that the products are still in a stable state after customers receive the goods, BLi-T Chemical chose fiber drum with sealed PE bags when choosing packaging. This is also one of the reasons why their shelf life can reach 2 years.
Combined Formulation Strategies
For comprehensive scalp care, Climbazole and Piroctone Olamine can be used together in a multi-functional formula or separately in distinct products. For instance, an anti-dandruff shampoo can incorporate Climbazole for its soothing and anti-inflammatory benefits, while Piroctone Olamine enhances antifungal action. Properly formulated, these ingredients can create a product that addresses multiple scalp issues, offering consumers a superior experience.
Both Climbazole (CAS No.: 38083-17-9, Chemical Formula: C15H17ClN2O2) and Piroctone Olamine (CAS No.: 68890-66-4, Chemical Formula: C16H30N2O3) are highly effective in treating dandruff and promoting scalp health. By understanding their properties, compatibility, and optimal formulation practices, manufacturers like BLi-T (Hefei) Chemical Co., Ltd. can develop superior anti-dandruff shampoos that stand out in the competitive hair care market. Whether you are formulating a new product or enhancing an existing one, these ingredients offer significant benefits for consumers seeking effective dandruff solutions.
